When EAGLE began, radio was still king and two of its most popular strips originated as BBC radio series. PC 49 began in 1947 and 112 half hour adventures of the London policeman, played by Brian Reece, were made before the programme ended in 1953. PC 49’s adventures began in the first issue of EAGLE and ran until 1957. The radio adventures of Riders of the Range, featuring Paul Carpenter as Jeff Arnold, began in 1949 and six serials were broadcast between 1949 and 1953, with the EAGLE version beginning in December 1950 and running till March 1962. Unlike strip versions of later television series in other comics, which were invariably notably inferior to their originals, the EAGLE versions of both these radio series compared most favourably, probably because they were written by their creators and illustrated by excellent artists in John Worsley and Frank Humphris, who made the strips their own. Their success is evidenced by the fact that both outlasted their radio counterparts by several years.
Of the characters who were specially created for EAGLE, Dan Dare featured in a hugely successful series of radio serials on Radio Luxembourg between 1951 and 1955, where he was played by Noel Johnson, who had originated the popular Dick Barton character in 1947, for BBC radio. The BBC produced their own four part Dan Dare serial in 1990 to mark EAGLE'S fortieth anniversary, which featured Mick Brown as Dan and Donald Gee as Digby. In 1954, EAGLE began its own promotional programme on Radio Luxembourg, called Spread Your Wings and this featured a six part Luck of the Legion serial, narrated by Norman Shelley as an old legionnaire. Sergeant Luck also appeared on the commercial Springbok Radio in South Africa in 1979 in his own series, written by his creator Geoffrey Bond, twenty years after the strip ended in EAGLE.